Tuesday, February 9, 2010

Mendelian laws also apply to humans

Did you know that a pedigree can be used to trace human genetic heredity? Click here to view an animation of a pedigree of the Queen of England (the part of the family leading up to the Russian Royal House - the Romanovs). You will see how the gene for hemophilia is passed on from one generation to the next.

What type of genetic disorder is hemophilia? Who can be a carrier? Who will be affected by this disease?

12 comments:

  1. i think that Queen Victoria of England's situation was pretty sad. i mean that you may never kno if you are the carrier or actually affected with it. Also this disease is a very fatal one. If you get a cut, you can lose a lot of blood and the technology and medecine at that time sucked!!! But tht was interesting. Thx leslie!!! I never knew this royal family had this type of problem!!!
    -Rachel

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  2. Cool animation! Why do traits such as diseases like hemophilia sometimes skip a generation but are then shown in the next generation?

    Caitlyn 7H

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  3. Wow!
    THat's so cool. Butit so complicated....

    Michael N. 7I

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  4. Wow, I had no idea that Queen Victoria had hemophilia running through her family, that's really interesting.
    Thanks Leslie!

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  5. This is really interesting. I thought it was really cool when the X chromosome passed down the family tree to show how it passed from the Queen to her descendants. Thanks Leslie!

    Julia G. ~ 7F

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  6. WOW!
    This was really interesting.
    Thanks for posting this Leslie.
    Leila 7F

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  7. This was very interesting but very tragic! Females were carriers and males were infected! :(
    Thanks for posting these interesting links, Leslie!

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  8. This is cool. I also looked at some of the other links on the right of that page... they are interesting too! I recommend for people to look at the animations as well. :)

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  9. oh, girls can be carriers and only boys can have hemophilia, my mommy is a hematologist and oncologist!

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  10. Wow this was really informative and fun. Just curious who figured all this out and how?

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  11. this "disease passing thru genes" suddenly makes more sense! i had already knew about hemophilia and the romanovs, because i had read a lot of books about them (including the "diary" of anastasia, the youngest daughter, who was rumored to have survived the shooting). the female carriers led very tragic lives (and also very famous ones), so a lot of historians and scientists studied the lives of the romanovs. even after they passed away, their family disease still interested many poeple. does that answer ur question, sarah?
    -emily lei 7H =]

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  12. if a guy got a disease, but then had it cured, would there still be the possibility that the offspring would still have that disease?
    -simon

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